| Primary Identifier | MGI:3511175 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Syngap1 |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neo cassette flanked by loxP sites inserted into intron 3 and an additional loxP site within exon 9 via homologous recombination. Expression of Cre recombinase in recombinant ES cells resulted in the deletion of exons 4-9. Western blot analysis confirmed the absence of protein in hippocampal homogenates at P0 and in hippocampal neurons cultured for 10 days. |
