| Primary Identifier | MGI:3511350 | Allele Type | Gene trapped |
| Attribute String | Null/knockout, Reporter | Gene | Myh9 |
| Transmission | Germline | Strain of Origin | 129S5/SvEvBrd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A gene trap vector containing a splice acceptor sequence, promotorless Betageo, pA, PGK, exon 1 from Btk and splice donor sequence, was inserted into intron 1 of the endogenous gene. Btk contained a stop codon in each reading frame to prevent translation of downstream fusion transcripts. Protein expression was reduced by half in heterozygotes as shown by immonoblot analysis. |
