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Allele : Rps6kb1<tm1Nte> ribosomal protein S6 kinase, polypeptide 1; targeted mutation 1, Naohiro Terada

Primary Identifier  MGI:3511860 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rps6kb1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette, inserted in opposite orientation, replaced the exon encoding amino acid residues 207-237 in the p70s6k protein. The downstream coding region was also frame shifted. Immunological analysis indicated the absence of activity for both the p70 and the p85 isoforms.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • p70<s6k>,
  • p85<s6k>,
  • p70<s6k>,
  • p85<s6k>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele