| First Author | Gaudot L | Year | 2018 |
| Journal | Eur J Immunol | Volume | 48 |
| Issue | 4 | Pages | 720-723 |
| PubMed ID | 29293266 | Mgi Jnum | J:261339 |
| Mgi Id | MGI:6151219 | Doi | 10.1002/eji.201747258 |
| Citation | Gaudot L, et al. (2018) Med1 deficiency alters the somatic hypermutation spectrum in murine B cells. Eur J Immunol 48(4):720-723 |
| abstractText | The Mediator complex is known to orchestrate transcription. Here we show that B cell conditional deficient mice for the Med1 subunit display robust somatic hypermutation. Nevertheless, the mutation frequency at A residues is decreased and the expected A/T ratio is abolished, implicating Mediator in the second phase of somatic hypermutation. |
