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Allele : Chrna4<tm2Lst> cholinergic receptor, nicotinic, alpha polypeptide 4; targeted mutation 2, Henry A Lester

Primary Identifier  MGI:3511287 Allele Type  Targeted
Attribute String  Not Specified Gene  Chrna4
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A point mutation was introduced to change a leucine to alanine within the putative pore-forming M2 domain. A loxP flanked neo cassette was also inserted in the construct. Correctly targeted ES cells were transfected with Cre plasmid to remove the neo.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • L9'A,
  • Leu9'Ala,
  • Leu9'Ala,
  • L9'A
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

9 Publication categories