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Allele : Sv2b<tm1Baj> synaptic vesicle glycoprotein 2b; targeted mutation 1, Sandra M Bajjalieh

Primary Identifier  MGI:3511830 Allele Type  Targeted
Attribute String  Null/knockout Gene  Sv2b
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin gene replaced the first coding exon and flanking sequences. Northern blot of of homozygote brain extracts indicated the presence of a truncated mRNA. Western blot analysis of brain homogenates derived from homozygous mice confirmed that no detectable encoded protein was made though the only available antibodies target the amino terminus.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

11 Publication categories