| Primary Identifier | MGI:3512754 | Allele Type | Chemically induced (other) |
| Attribute String | Null/knockout | Gene | Rec8 |
| Inheritance Mode | Recessive | Transmission | Germline |
| Strain of Origin | (C57BL/6J x 129S4/SvJae)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | ES cells were mutagenized using ethyl methansulfonate (EMS), leading to a C-to-T nonsense mutation (GRCm39:chr14:g.55857155C>T) that changes glutamine codon 155 (CAG) in exon 6 (out of 20) to a stop codon (TAG) (p.Q155*). RT-PCR of testes samples from mutants confirmed the lack of transcripts from this allele. |
