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Allele : Htra2<tm1Jdo> HtrA serine peptidase 2; targeted mutation 1, Julian Downward

Primary Identifier  MGI:3512633 Allele Type  Targeted
Attribute String  Null/knockout Gene  Htra2
Transmission  Germline Strain of Origin  129P/Ola
Is Recombinase  false Is Wild Type  false
molecularNote  A PGK-neo gene replaced part of exon 1, exons 2 to 6, and part of exon 7 via homologous recombination, removing 83% of the coding sequence including the proteolytic catalytic site. Western blot analysis confirmed absence of protein in MEFs
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • HtrA2/Omi<->,
  • HtrA2/Omi<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories