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Allele : Tgfb1<tm1Jmu> transforming growth factor, beta 1; targeted mutation 1, John Munger

Primary Identifier  MGI:3513111 Allele Type  Targeted
Attribute String  Inserted expressed sequence, Null/knockout Gene  Tgfb1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette was inserted in the intron between exons 5 and 6. In exon 5, a mutation was introduced that changes a D codon to an E codon (p.D246E); this mutates the RGD integrin binding site in the propeptide to RGE.
  • mutations:
  • Insertion
  • synonyms:
  • Tgfb1<RGE>,
  • Tgfb1<RGE>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories