Primary Identifier | MGI:3521583 | Allele Type | Targeted |
Attribute String | Conditional ready, Hypomorph | Gene | Pkd1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This is a hypomorphic allele created by the insertion of a loxP-flanked neo into intron 1 and a third loxP site into intron 11. The neo causes aberrant splicing of intron 1, yielding 13-20% normally spliced transcripts in the majority of mutant mice. |