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Transgene : Tg(KRT14-HPV16E6)5737Plam transgene insertion 5737, Paul F Lambert
Primary Identifier  MGI:3618907 Organism  mouse, laboratory
Chromosome  UN Mgi Type  transgene
description  PHENOTYPE: All mice of this transgenic line have cataracts and develop thickening of the ears. 7% of mice hemizygous for the transgene and >20% of homozygotes develop skin tumors on their torsos and/or limbs by 1 year of age; ~14% of hemizygotes exhibit tumors by 15 months. Most of the tumors are malignant. [provided by MGI curators]
  • synonyms:
  • Tg(KRT14-HPV16E6)5737Plam,
  • K14E6,
  • K14-E6,
  • K14E6<WT>,
  • 5737,
  • K14E6 5737,
  • transgene insertion 5737, Paul F Lambert
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