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Allele : Adam10<tm1Psa> a disintegrin and metallopeptidase domain 10; targeted mutation 1, Paul Saftig

Primary Identifier  MGI:3522353 Allele Type  Targeted
Attribute String  Null/knockout Gene  Adam10
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The 5' exon was interrupted by the insertion of a neomycin expression cassette. This introduces a premature stop codon into the ORF. RT-PCR and Northern blot analysis confirmed the absence of transcription. Western blot analysis demonstrated the absence of a protein product.
  • mutations:
  • Insertion
  • synonyms:
  • Adam10<->,
  • Adam10<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

15 Publication categories