Primary Identifier | MGI:3525058 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(KRT5-SMO*W535L)#Fjs |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A human SMO cDNA with a Trp to Leu mutation at codon 535 was cloned downstream of the human KRT5 promoter. Enhancer and polyA sequences were contributed by SV40. Transgene expression was directed toward the basal cell layer of transgenic skin. No postnatal data exist for this allele. |