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Allele : Nkx6-2<tm1Gow> NK6 homeobox 2; targeted mutation 1, Alexander Gow

Primary Identifier  MGI:3522433 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Nkx6-2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A fragment of sequence containing the ORF in exons 1 and 2 was replaced with a lacZ-PGK-neo cassette. Northern blot of mutant brains indicated a lack of Nkx6-2 transcript, however, two signals were observed that hybridized to a lacZ probe. X-gal staining demonstrated lacZ was expressed prenatally in neurons and postnatally in oligodendrocytes of mutant embryos.
  • mutations:
  • Insertion
  • synonyms:
  • Nkx6-2<->,
  • Nkx6-2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele