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Allele : Prkce<tm1Bai> protein kinase C, epsilon; targeted mutation 1, Gottfried Baier

Primary Identifier	MGI:3524969	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Prkce
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

A neomycin resistance gene was inserted into exon 1. Immunostaining confirmed the lack of protein in mutant thymocytes. Flow cytometry indicated that thymocyte numbers and development appeared to be unaffected by the mutation.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
PKCepsilon<->,
PKCepsilon<->

earliestPublication:
Gruber T, et al. (2005) Protein kinase Cvarepsilon is dispensable for TCR/CD3-signaling. Mol Immunol 42(3):305-310

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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