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Allele : Sgk3<tm1Dpea> serum/glucocorticoid regulated kinase 3; targeted mutation 1, David Pearce

Primary Identifier  MGI:3524987 Allele Type  Targeted
Attribute String  Null/knockout Gene  Sgk3
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by the deletion of part of exons 9 and 10 containing the ATP-binding site necessary for catalytic activity, and introducing an in-frame stop codon into exon 10. Northern blot of kidney, lung and thymus of mutants showed a lack of mRNA, and Western blot of kidney and liver confirmed a null protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Sgk3<->,
  • Sgk3<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

13 Publication categories