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Allele : Hdac4<tm1Eno> histone deacetylase 4; targeted mutation 1, Eric N Olson
Primary Identifier  MGI:3525071 Allele Type  Targeted
Attribute String  Null/knockout Gene  Hdac4
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 6 was replaced upon the insertion of an nLacZ-neo cassette in frame with amino acid 162. The deleted region encodes the nuclear localization sequence and the complete deacetylase catalytic domain. Mutant heart and brain samples demonstrated a lack of wild-type mRNA by RT-PCR analysis.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • HDAC4<->,
  • HDAC4<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

14 Publication categories





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