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Allele : Aph1b<tm1Bdes> aph1 homolog B, gamma secretase subunit; targeted mutation 1, Bart De Strooper

Primary Identifier  MGI:3522628 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Aph1b
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert a modified human placental alkaline phosphatase reporter sequence, polyA signal at the ATG in exon 1. RT-PCR and Western blot of mutant MEFs demonstrated the expression of mRNA or protein, respectively.
  • mutations:
  • Insertion
  • synonyms:
  • Aph1b<->,
  • Aph1b<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

10 Publication categories