Primary Identifier | MGI:3522638 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(RBP3-TAg)#Ove |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
description | This mutation is representative of 4 transgenic founders (413, 414, 417, 437) carrying 2-9 copies of the trangene. All founders exhibit brain and eye tumors at a high incidence of 63%-100%. |
molecularNote | A 1.3 kb fragment of the human RBP3 gene including promoter and transcription start site was used to direct expression of the SV40 T antigen and polyA sequences. |