Primary Identifier | MGI:3522718 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Upk2-HRAS*Q61L)12Xrw |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This transgene included a 3.6 kb fragment encoding the murine Upk2 gene promoter placed upstream of a 3.0 kb sequence encoding a mutant rabbit Hras gene (glutamine to leucine point mutation at codon 61). Mice carrying this allele generated 2 transgene fragments measuring 4.9 and 8.2 kb in length, representing head to tail and tail to tail arrangements, respectively. Approximately 30 copies of the transgene were inserted into the genome. |