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Allele : Tg(Upk2-HRAS*Q61L)12Xrw transgene insertion 12, Xue-Ru Wu

Primary Identifier  MGI:3522718 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Upk2-HRAS*Q61L)12Xrw
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene included a 3.6 kb fragment encoding the murine Upk2 gene promoter placed upstream of a 3.0 kb sequence encoding a mutant rabbit Hras gene (glutamine to leucine point mutation at codon 61). Mice carrying this allele generated 2 transgene fragments measuring 4.9 and 8.2 kb in length, representing head to tail and tail to tail arrangements, respectively. Approximately 30 copies of the transgene were inserted into the genome.
  • mutations:
  • Insertion
  • synonyms:
  • UPII/Ha-ras 12,
  • UPII/Ha-ras 12
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories