| Primary Identifier | MGI:3525161 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(H2-k-Polb/Sh)8Cca |
| Strain of Origin | (CBA x C57BL/6)F2 | Is Recombinase | false |
| Is Wild Type | false |
| description | Hemizygous transgenic mice show no phenotype, while homozygous mice (25/69) showed premature death due to unknown causes. |
| molecularNote | The promoter for the murine MHC class I H-2K gene directed the expression of a rat Polb cDNA fragment to the thymus. Enhancer and polyA sequences were donated by the rabbit Beta-globin gene. Transgene expression was detected in the thymus, but not in the spleen, kidney, heart, lung, liver, intestine, or testis. |
