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Allele : Nkx2-1<tm1Rdl> NK2 homeobox 1; targeted mutation 1, Roberto Di Lauro

Primary Identifier  MGI:3525207 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Nkx2-1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A sequence from rat Foxe1 replaced the endogenous sequence spanning from the start site to the end of the homeobox (nucleotide positions 7957 to 9480). Sv40 pA was added after the stop codon, as well as a PGK-neo cassette. The inserted sequence was ectopically expressed in Titf1 expression domains like the lung and diencephalons,
  • mutations:
  • Insertion
  • synonyms:
  • Titf1<Foxe1>,
  • Titf1<Foxe1>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

5 Publication categories