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Allele : Mapk14<tm1.1Otsu> mitogen-activated protein kinase 14; targeted mutation 1.1, Kinya Otsu

Primary Identifier	MGI:3525575	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Mapk14
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

Cre mediated excision deleted the exon encoding part of the catalytic domain and the ATP binding loop (amino acids 40-83).

mutations:
Intragenic deletion

cellLines:
Not Specified

synonyms:
p38alpha<->,
p38alpha<->

earliestPublication:
Nishida K, et al. (2004) p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload. Mol Cell Biol 24(24):10611-20

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

8 Publication categories

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