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Allele : Erbb2<tm8(Erbb2)Mul> erb-b2 receptor tyrosine kinase 2; targeted mutation 8, William J Muller

Primary Identifier  MGI:3525444 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence Gene  Erbb2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 1 of the endogenous Erbb2 allele was replaced by a lox-P flanked PGK-neomycin-HSV polyA cassette, followed by an oncogenic Erbb2 cDNA containing an activating point mutation in the transmembrane domain.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • ErbB2<KI>,
  • ErbB2<KI>,
  • NeuNT,
  • NeuNT,
  • neuNT<ki>,
  • Flneo NeuNT,
  • neuNT<ki>,
  • Flneo NeuNT
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

24 Publication categories