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Allele : Umod<tm1Xrw> uromodulin; targeted mutation 1, Xue-Ru Wu

Primary Identifier  MGI:3526897 Allele Type  Targeted
Attribute String  Null/knockout Gene  Umod
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 1-4 and a 650 bp proximal promoter region were replaced with a neomycin cassette. RT-PCR and Northern blot analysis demonstrated the lack of transcript in mutant kidneys. Immunohistochemistry and Western blot showed that no protein was present in mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • THP<->,
  • THP<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

18 Publication categories