Primary Identifier | MGI:3526897 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Umod |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 1-4 and a 650 bp proximal promoter region were replaced with a neomycin cassette. RT-PCR and Northern blot analysis demonstrated the lack of transcript in mutant kidneys. Immunohistochemistry and Western blot showed that no protein was present in mutant mice. |