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Allele : Tg(Pim1-E2F1)5Rebr transgene insertion 5, Rene Bernards

Primary Identifier	MGI:3527138	Allele Type	Transgenic
Attribute String	Humanized sequence, Inserted expressed sequence	Gene	Tg(Pim1-E2F1)5Rebr
Strain of Origin	FVB/N	Is Recombinase	false
Is Wild Type	false

molecularNote

A human E2F1 cDNA was cloned downstream of a murine Pim1 promoter in which a duplicated Ig heavy chain enhancer sequence was inserted. The polyA sequence was contributed by the Molony murine leukemia virus.

mutations:
Insertion

synonyms:
TEF1-5,
Eu-pp-E2F1,
Eu-pp-E2F1,
TEF1-5

earliestPublication:
Scheijen B, et al. (2004) High incidence of thymic epithelial tumors in E2F2 transgenic mice. J Biol Chem 279(11):10476-83

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

1 Driven By

2 Publication categories

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