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Allele : Tg(Pim1-E2F2)35Rebr transgene insertion 35, Rene Bernards

Primary Identifier	MGI:3527140	Allele Type	Transgenic
Attribute String	Humanized sequence, Inserted expressed sequence	Gene	Tg(Pim1-E2F2)35Rebr
Strain of Origin	FVB/N	Is Recombinase	false
Is Wild Type	false

molecularNote

A human E2F2 cDNA was cloned downstream of a murine Pim1 promoter in which a duplicated immunoglobulin heavy chain enhancer sequence was inserted. The polyA sequence was contributed by the Molony murine leukemia virus.

mutations:
Insertion

synonyms:
Eu-pp-E2F2,
TEF2-33,
TEF2-33,
Eu-pp-E2F2

earliestPublication:
Scheijen B, et al. (2004) High incidence of thymic epithelial tumors in E2F2 transgenic mice. J Biol Chem 279(11):10476-83

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

1 Driven By

2 Publication categories

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