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Allele : Tnf<tm1.1Sned> tumor necrosis factor; targeted mutation 1.1, Sergei A Nedospasov

Primary Identifier  MGI:3527143 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Tnf
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin selection cassette was inserted approximately 1 kb downstream of the gene and a third loxP site was inserted in the 3rd intron. The neomycin resistance cassette was subsequently removed by transient cre expression in ES cells. The remaining loxP sites had no effect on gene expression or phenotype.
  • mutations:
  • Insertion
  • synonyms:
  • Tnf<tm1Sned>,
  • TNF<flox>,
  • Tnf<tm1Sned>,
  • TNF<flox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

32 Publication categories