| Primary Identifier | MGI:3527155 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Smad2 |
| Transmission | Germline | Strain of Origin | 129S/SvEv-Gpi1<c> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A floxed PGK-neo replaced a 488-bp fragment containing the alternatively spliced exon 3. Expression of a cre vector excised the floxed neo, leaving a single loxP site in place of exon 3. Expression of transcript lacking exon 3 was increased compared to wild-type and full length mRNA was undetectable in mutant animals. |
