Primary Identifier | MGI:3527221 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Igh-V186.2-TCL1A)3Cro |
Strain of Origin | C57BL/6 x C3H | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A 350 bp fragment encoding the entire human TCL1A coding region was placed under the transcriptional control of the mouse Igh-V186.2 promoter and the Igh-mu enhancer sequence. 3'UTR and polyA sequences were derived from the human Beta-globin gene. Transgene expression was detected in the spleen and bone marrow, but not the liver. |