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Allele : Tgm2<tm1.1Rmgr> transglutaminase 2, C polypeptide; targeted mutation 1.1, Robert M Graham

Primary Identifier  MGI:3527996 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tgm2
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 6-8 were excised following cre-mediated excision. This sequence encoded the TGase catalytic core domain. Northern blot and RT-PCR both confirmed absence of transcript in mutant hearts. Lack of protein was demonstrated in mutant liver membranes and heart cytosol by Western blot analysis.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Tgm2<->,
  • Tgm2<->,
  • TG2<->,
  • TG2<->,
  • TGase 2-,
  • TGase 2-,
  • tTg<->,
  • tTg<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

30 Publication categories

Trail: Allele