| Primary Identifier | MGI:3528447 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Aqp11 |
| Transmission | Germline | Strain of Origin | 129S5/SvEvBrd |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Lexicon |
| molecularNote | A targeting construct was designed to delete exons 2 and 3, corresponding to the second NPA box of the locus, and replace them with an IRES-beta-gal-MC1-neo cassette. Northern blot of mutants demonstrated lack of transcript in kidney and liver samples. Western blot and immunohistochemistry confirmed absence of protein in mutant kidney samples. |
