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Allele : Nod2<tm1Flv> nucleotide-binding oligomerization domain containing 2; targeted mutation 1, Richard A Flavell
Primary Identifier  MGI:3529594 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nod2
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP-flanked neo replaced exon 3, encoding the CARD domain and P-loop of the NOD domain. Spleens of mutant animals demonstrated a lack of protein by immunoblot analysis.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Nod2<->,
  • Nlrc2<->,
  • Nlrc2<->,
  • Nod2<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

150 Publication categories





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