Primary Identifier | MGI:3529870 | Allele Type | QTL |
Gene | Nba10 | Inheritance Mode | Not Specified |
Strain of Origin | NZB | Is Recombinase | false |
Is Wild Type | false |
description | This allele shows linkage to increased anti-chromatin and anti-DNA antibodies, increased serum gp70 immune complex levels, and severe glomerulonephritis. |
molecularNote | This allele confers increased susceptibility to autoimmunity compared to C57BL/6. |