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Allele : Lama1<tm1.1Ekb> laminin, alpha 1; targeted mutation 1.1, Peter Ekblom

Primary Identifier	MGI:3530457	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Lama1
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

ES cells containing Lama1^tm1Ekb were transfected with cre recombinase, resulting in the excision of the neo-HSV-tk cassette. A truncated protein was detected by immunoblots of ES cells.

mutations:
Disruption caused by insertion of vector

cellLines:
Not Specified

synonyms:
AlphaILG4-5<->,
AlphaILG4-5<->

earliestPublication:
Scheele S, et al. (2005) Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly. Proc Natl Acad Sci U S A 102(5):1502-6

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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