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Allele : Kdr<tm2.1Msh> kinase insert domain protein receptor; targeted mutation 2.1, Masabumi Shibuya

Primary Identifier  MGI:3530469 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Kdr
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to introduce substitution Y1212F (TAT to TTC) into exon 27. Crossing with mice expressing cre in the germ line deleted a floxed neo from intron 26. Western blot of mutant lung lysates demonstrated protein expression levels were similar to that of wild-type.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Flk-1<1212F>,
  • Flk-1<1212F>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories