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Allele : Nod2<tm1Mka> nucleotide-binding oligomerization domain containing 2; targeted mutation 1, Michael Karin

Primary Identifier  MGI:3530578 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nod2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A cytosine was inserted at 2939 in exon 11 of the ORF, resulting in a frame-shift leading to a premature stop codon and a truncated protein. The targeting vector contained a neo downstream of the inserted cytosine. RT-PCR and Western blot confirmed successful recombination.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Nod2<2939>,
  • Nod2<mt>,
  • Nod2<mt>,
  • Nod2<2939>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories