Primary Identifier | MGI:3530578 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Nod2 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A cytosine was inserted at 2939 in exon 11 of the ORF, resulting in a frame-shift leading to a premature stop codon and a truncated protein. The targeting vector contained a neo downstream of the inserted cytosine. RT-PCR and Western blot confirmed successful recombination. |