First Author | Jacobson AC | Year | 2007 |
Journal | Infect Immun | Volume | 75 |
Issue | 4 | Pages | 2075-8 |
PubMed ID | 17283093 | Mgi Jnum | J:119763 |
Mgi Id | MGI:3703229 | Doi | 10.1128/IAI.01920-06 |
Citation | Jacobson AC, et al. (2007) Mice lacking CD21 and CD35 proteins mount effective immune responses against Borrelia burgdorferi infection. Infect Immun 75(4):2075-8 |
abstractText | CD21/35(-/-) mice, deficient in CD21 and CD35 (complement receptors 2 and 1, respectively), were infected with Borrelia burgdorferi to assess the role of these receptors in a chronic bacterial infection. Although CD21/35(-/-) mice on both C57BL/6 and BALB/c backgrounds produced less B. burgdorferi-specific antibodies than did wild-type mice, spirochete levels and arthritis severity were similar. |