| Primary Identifier | MGI:3573744 | Allele Type | Spontaneous |
| Gene | Clcn1 | Inheritance Mode | Recessive |
| Strain of Origin | B6;129S-Fcgr2b<tm1Ttk> | Is Recombinase | false |
| Is Wild Type | false |
| description | Mice homozygous for Clcn1adr-mto5J are affected by a neuromuscular disorder that manifests by weaning as an apparent weakness or stiffness in the rear legs, which is particularly noticeable when the mice are picked up and put down again (as when being transferred to a new cage). The phenotype may disappear as the mice get older. Both male and female homozygotes have normal lifespans and are fertile. |
| molecularNote | This mutation occurred spontaneously in a colony at The Jackson Laboratory in October, 1999. It was shown to be a remutation at Clcn1 by its failure to complement Clcn1adr-mto2J in a complementation test. |
