Primary Identifier | MGI:3573870 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cdh17 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 16-18, which encode the transmembrane and cytoplasmic domain, were replaced with a neomycin resistance cassette. Surface labeling and subsequent immunoprecipitation demonstrated the complete absence of protein on surface of B lineage cells. |