| Primary Identifier | MGI:1095414 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 12557 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables proton-dependent oligopeptide secondary active transmembrane transporter activity. Involved in germinal center B cell differentiation; marginal zone B cell differentiation; and spleen development. Acts upstream of or within calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; and oligopeptide transport. Located in cell surface and plasma membrane. Is expressed in several structures, including common bile duct; genitourinary system; gut; spleen; and trunk. Orthologous to human CDH17 (cadherin 17). PHENOTYPE: Homozygous mutant mice exhibit impaired B lymphocyte development and impaired IgG1 and IgG3 antibody response to T-independent antigen. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
