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Allele : Dclre1c<tm2Mcow> DNA cross-link repair 1C; targeted mutation 2, Morton J Cowan

Primary Identifier	MGI:3574021	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Dclre1c
Transmission	Germline	Strain of Origin	129
Is Recombinase	false	Is Wild Type	false

molecularNote

Exons 6-11, encompassing 80% of the gene, were replaced with a neo. Western blot of lymphoid tissues demonstrated the lack of wild-type protein in mutants.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
mArt<->,
mArt<->

earliestPublication:
Li L, et al. (2005) Targeted disruption of the artemis murine counterpart results in SCID and defective V(D)J recombination that is partially corrected with bone marrow transplantation. J Immunol 174(4):2420-8

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

5 Publication categories

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