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Allele : Ehmt1<tm1Yshk> euchromatic histone methyltransferase 1; targeted mutation 1, Yoichi Shinkai

Primary Identifier	MGI:3575505	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Ehmt1
Transmission	Germline	Strain of Origin	(C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase	false	Is Wild Type	false

molecularNote

A targeting vector was designed to replace exon 5 and part of exon 6 with a neomycin resistance gene. The deleted sequence encodes the catalytic core region of the SET domain.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
GLP<->,
GLP<->

earliestPublication:
Tachibana M, et al. (2005) Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9. Genes Dev 19(7):815-26

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

15 Publication categories

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