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Allele : Septin4<tm1Hs> septin 4; targeted mutation 1, Hermann Steller

Primary Identifier	MGI:3574368	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Septin4
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

8 kb of sequence, almost the entire locus, was replaced with a neomycin resistance gene. Western blot confirmed the absence of isoforms H5 and M-Septin by probing cerebellum protein extracts from mutants with an antibody raised against a peptide from exon 1.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Sept4<->,
Sept4<->

earliestPublication:
Kissel H, et al. (2005) The Sept4 septin locus is required for sperm terminal differentiation in mice. Dev Cell 8(3):353-64

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

3 Carried By

0 Driven By

8 Publication categories

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