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Allele : Hrk<tm1Nnz> harakiri, BCL2 interacting protein (contains only BH3 domain); targeted mutation 1, Gabriel Nunez

Primary Identifier	MGI:3574591	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Hrk
Transmission	Germline	Strain of Origin	129/Sv
Is Recombinase	false	Is Wild Type	false

molecularNote

The single coding exon was replaced with a neomycin resistance cassette. RT-PCR of mutant brain, spleen, thymus, bone marrow and liver samples demonstrated the lack of transcript.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
DP5<->,
DP5<->

earliestPublication:
Imaizumi K, et al. (2004) Critical role for DP5/Harakiri, a Bcl-2 homology domain 3-only Bcl-2 family member, in axotomy-induced neuronal cell death. J Neurosci 24(15):3721-5

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

8 Publication categories

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