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Publication : Nuclear hormone receptors and mouse skin homeostasis: implication of PPARbeta.

First Author  Michalik L Year  2000
Journal  Horm Res Volume  54
Issue  5-6 Pages  263-8
PubMed ID  11595815 Mgi Jnum  J:102791
Mgi Id  MGI:3608074 Doi  10.1159/000053269
Citation  Michalik L, et al. (2000) Nuclear hormone receptors and mouse skin homeostasis: implication of PPARbeta. Horm Res 54(5-6):263-8
abstractText  PPARbeta is expressed in the mouse epidermis during fetal development, and progressively disappears from the interfollicular epidermis after birth. Interestingly, its expression is strongly reactivated in the adult epidermis in conditions where keratinocyte proliferation is induced and during wound healing. Data obtained on PPARbeta heterozygous mice reveal that PPARbeta is implicated in the control of keratinocyte proliferation and is necessary for rapid healing of a skin wound.
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