| Primary Identifier | MGI:3577898 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Stat5b |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| description | ES cell line = E14 (129P2/OlaHsd) or RW4 (129X1/SvJ). |
| molecularNote | The first coding exon was replaced by a neomycin resistance cassette via homologous recombination in an ES cell line in which the first two coding exons of Stat5a had already been replaced with a hygromycin resistance cassette. This ES cell line was previously used to produce the Stat5atm1Jni mouse. The Stat5b targeting vector is the same one used to produce the Stat5btm1Jni allele. N-terminally truncated proteins are found at significant levels in the lymphoid lineage by Western Blot analysis (J: 122463). |
