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Allele : Dicer1<tm1Gz> dicer 1, ribonuclease type III; targeted mutation 1, Genshi Zhao

Primary Identifier  MGI:3576927 Allele Type  Targeted
Attribute String  Hypomorph Gene  Dicer1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 1 and 2 were replaced with a neomycin resistance gene to create this severely hypomorphic allele. Although a transcript from these two exons was not present in Northern blot analyses, a transcript originating from exon 3 was found. Western blot demonstrated the presence of a nonfunctional protein product probably originating from exon 4.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Dicer<ex1/2>,
  • Dicer<ex1/2>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele