First Author | Miyazawa M | Year | 1992 |
Journal | Eur J Immunogenet | Volume | 19 |
Issue | 3 | Pages | 159-64 |
PubMed ID | 1627536 | Mgi Jnum | J:1094 |
Mgi Id | MGI:49626 | Doi | 10.1111/j.1744-313x.1992.tb00054.x |
Citation | Miyazawa M, et al. (1992) Detailed mapping of the Rfv-1 gene that influences spontaneous recovery from Friend retrovirus-induced leukaemia. Eur J Immunogenet 19(3):159-64 |
abstractText | Using H-2 recombinant and mutant mice, the Rfv-1 gene influencing spontaneous recovery from Friend retrovirus (FV)-induced leukaemia was mapped in the D locus. Two Db alleles were required for full recovery, and a single Dd transgene did not convey increased susceptibility to FV in the presence of homozygous Db/b genotype. The results suggest that an increase in the expression of Db may lead to more effective stimulation of FV-specific CTL. |