Primary Identifier | MGI:3577064 | Organism | mouse, laboratory |
Chromosome | 1 | Mgi Type | heritable phenotypic marker |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Used to study neurodegeneration with brain iron accumulation 2a. PHENOTYPE: Homozygous mutant mice die before sexual maturity and exhibit axonal dystrophic change appearing as spheroid bodies in the nervous system. Mice show progressive motor paralysis and atrophy of the hindlimbs. [provided by MGI curators] |